:root {
  --bg: #f4fafa;
  --fg: #0f172a;
  --mut: #4b5563;
  --card: #ffffff;
  --line: #d9e2e7;
  --acc: #0b6e7f;
  --warn: #fff8e6;
  --warnl: #ead79a;
  --bad: #a4261d;
}

html {
  scroll-behavior: smooth;
  scroll-padding-top: 82px;
}

* {
  box-sizing: border-box;
}

body {
  min-width: 0;
  margin: 0;
  overflow-x: hidden;
  background: var(--bg);
  color: var(--fg);
  font-family: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  font-size: 16px;
  line-height: 1.7;
}

.wrap {
  width: min(100% - 40px, 1120px);
  max-width: 1120px;
  margin: 0 auto;
  padding: 24px 0 72px;
}

.wrap h1 {
  margin: 12px 0 4px;
  font-size: clamp(2rem, 4vw, 2.55rem);
  line-height: 1.15;
  letter-spacing: -0.025em;
}

.wrap > .sub {
  max-width: 820px;
  margin: 0 0 12px;
  color: var(--mut);
  font-size: 1rem;
  line-height: 1.6;
  overflow-wrap: anywhere;
}

.drug-breadcrumbs {
  display: flex;
  flex-wrap: wrap;
  align-items: center;
  gap: 8px;
  margin: 0 0 16px;
  color: var(--mut);
  font-size: 0.9rem;
  line-height: 1.4;
}

.drug-breadcrumbs a {
  color: var(--acc);
  text-decoration: none;
}

.drug-breadcrumbs a:hover {
  text-decoration: underline;
}

.drug-breadcrumbs [aria-hidden="true"] {
  color: #8b98a5;
}

.drug-summary {
  max-width: 820px;
  margin: 16px 0 20px;
  padding: 14px 18px;
  border-left: 3px solid var(--acc);
  border-radius: 0 10px 10px 0;
  background: color-mix(in srgb, var(--acc) 8%, var(--card));
  font-size: 1.04rem;
  line-height: 1.6;
}

.drug-summary strong {
  color: var(--acc);
}

.drug-jump-nav {
  position: sticky;
  z-index: 20;
  top: 0;
  display: flex;
  flex-wrap: nowrap;
  gap: 8px;
  width: 100%;
  margin: 18px 0 24px;
  padding: 10px 4px;
  overflow-x: auto;
  overscroll-behavior-x: contain;
  border-block: 1px solid var(--line);
  background: color-mix(in srgb, var(--bg) 94%, transparent);
  scrollbar-width: thin;
  -webkit-overflow-scrolling: touch;
  backdrop-filter: blur(12px);
}

.drug-jump-nav a {
  flex: 0 0 auto;
  padding: 7px 13px;
  border: 1px solid transparent;
  border-radius: 999px;
  background: transparent;
  color: var(--mut);
  font-size: 0.92rem;
  font-weight: 600;
  line-height: 1.3;
  text-decoration: none;
  white-space: nowrap;
}

.drug-jump-nav a:hover,
.drug-jump-nav a:focus-visible {
  border-color: var(--line);
  color: var(--acc);
  outline-color: var(--acc);
}

.drug-jump-nav a[aria-current="location"] {
  background: color-mix(in srgb, var(--acc) 13%, var(--card));
  color: var(--acc);
}

.wrap > section {
  width: min(100%, 760px);
  margin: 20px auto;
  padding: 24px;
  overflow: hidden;
  border: 1px solid var(--line);
  border-radius: 16px;
  background: var(--card);
  box-shadow: 0 2px 10px rgb(15 23 42 / 4%);
  scroll-margin-top: 88px;
}

.wrap > #s-quick_facts {
  padding: 0;
}

.drug-quick-facts > summary {
  position: relative;
  padding: 20px 54px 20px 24px;
  color: var(--fg);
  cursor: pointer;
  list-style: none;
}

.drug-quick-facts > summary:focus-visible,
.drug-faq-item > summary:focus-visible,
.drug-source-details > summary:focus-visible {
  outline: 3px solid var(--acc);
  outline-offset: 3px;
}

.drug-quick-facts > summary::-webkit-details-marker {
  display: none;
}

.drug-quick-facts > summary > [role="heading"] {
  font-size: 1.35rem;
  font-weight: 700;
  line-height: 1.35;
}

.drug-quick-facts > summary::after {
  position: absolute;
  top: 28px;
  right: 26px;
  width: 9px;
  height: 9px;
  border-right: 2px solid var(--acc);
  border-bottom: 2px solid var(--acc);
  content: "";
  transform: rotate(45deg);
}

.drug-quick-facts[open] > summary {
  border-bottom: 1px solid var(--line);
}

.drug-quick-facts[open] > summary::after {
  top: 32px;
  transform: rotate(225deg);
}

.drug-quick-facts-content {
  padding: 4px 24px 20px;
}

.wrap > section > h2 {
  margin: 0 0 16px;
  padding-bottom: 12px;
  border-bottom: 1px solid var(--line);
  color: var(--fg);
  font-size: 1.5rem;
  font-weight: 700;
  line-height: 1.3;
  letter-spacing: -0.015em;
}

.wrap h3 {
  margin: 22px 0 8px;
  font-size: 1.2rem;
  line-height: 1.4;
}

.wrap p,
.wrap li {
  overflow-wrap: anywhere;
}

.wrap a {
  color: var(--acc);
  text-underline-offset: 0.16em;
}

.wrap .kv {
  grid-template-columns: minmax(125px, 170px) minmax(0, 1fr);
  gap: 6px 16px;
  min-width: 0;
  padding: 10px 0;
  overflow-wrap: anywhere;
}

.wrap .kv > *,
.wrap .kv .v,
.wrap .kv .k {
  min-width: 0;
  max-width: 100%;
  overflow-wrap: anywhere;
  word-break: normal;
}

.wrap .kv .k {
  color: var(--mut);
  font-size: 0.92rem;
  font-weight: 600;
}

.wrap .kv .v {
  line-height: 1.65;
}

.wrap .plain {
  line-height: 1.75;
}

.wrap .item {
  padding: 14px 0;
}

.drug-faq-item {
  border-bottom: 1px solid var(--line);
}

.drug-faq-item:last-child {
  border-bottom: 0;
}

.drug-faq-item > summary {
  position: relative;
  padding: 14px 28px 14px 0;
  color: var(--fg);
  font-size: 1.05rem;
  font-weight: 650;
  line-height: 1.5;
  list-style: none;
}

.drug-faq-item > summary::-webkit-details-marker {
  display: none;
}

.drug-faq-item > summary::after {
  position: absolute;
  right: 3px;
  width: 8px;
  height: 8px;
  border-right: 2px solid var(--acc);
  border-bottom: 2px solid var(--acc);
  content: "";
  transform: rotate(45deg);
  transition: transform 140ms ease;
}

.drug-faq-item[open] > summary::after {
  transform: rotate(225deg);
}

.drug-faq-answer {
  padding: 0 0 16px;
}

.drug-source-details {
  margin: 14px 0 0;
  border-top: 1px solid var(--line);
  color: var(--mut);
  font-size: 0.92rem;
}

.drug-source-details > summary {
  padding: 12px 0 2px;
  color: var(--acc);
  font-weight: 600;
  cursor: pointer;
}

.drug-source-details .kv {
  border-color: color-mix(in srgb, var(--line) 75%, transparent);
  font-size: 0.9rem;
}

.wrap table {
  display: block;
  max-width: 100%;
  overflow-x: auto;
  border-collapse: collapse;
  overflow-wrap: anywhere;
  -webkit-overflow-scrolling: touch;
}

.wrap td,
.wrap th {
  overflow-wrap: anywhere;
  word-break: normal;
}

.wrap details:not(.drug-faq-item):not(.drug-source-details) {
  margin: 12px 0;
}

.wrap details:not(.drug-faq-item):not(.drug-source-details) > summary {
  color: var(--acc);
  font-weight: 600;
}

.wrap .src {
  max-width: 100%;
  overflow-wrap: anywhere;
  word-break: normal;
}

.wrap .banner {
  border-radius: 12px;
}

.wrap > .banner {
  width: min(100%, 760px);
  margin: 16px auto;
}

.wrap .foot {
  width: min(100%, 760px);
  margin: 24px auto 0;
  line-height: 1.6;
}

@media (max-width: 640px) {
  .wrap {
    width: 100%;
    padding: 18px 12px 48px;
  }

  .wrap h1 {
    margin-top: 8px;
    font-size: 2rem;
  }

  .wrap > .sub {
    font-size: 0.96rem;
  }

  .drug-summary {
    padding: 12px 14px;
    font-size: 1rem;
  }

  .drug-jump-nav {
    width: calc(100% + 24px);
    margin: 14px -12px 18px;
    padding: 9px 12px;
  }

  .drug-jump-nav a {
    padding: 7px 11px;
    font-size: 0.88rem;
  }

  .wrap > section {
    width: 100%;
    margin: 14px auto;
    padding: 18px 16px;
    border-radius: 14px;
  }

  .wrap > #s-quick_facts {
    padding: 0;
  }

  .drug-quick-facts > summary {
    padding: 17px 48px 17px 17px;
  }

  .drug-quick-facts > summary::after {
    top: 25px;
    right: 20px;
  }

  .drug-quick-facts[open] > summary::after {
    top: 29px;
  }

  .drug-quick-facts-content {
    padding: 2px 16px 16px;
  }

  .wrap > section > h2 {
    font-size: 1.32rem;
  }

  .wrap .kv {
    grid-template-columns: minmax(0, 1fr);
    gap: 2px;
    padding: 10px 0;
  }

  .wrap .kv .k {
    padding-bottom: 1px;
    font-size: 0.86rem;
  }

  .drug-faq-item > summary {
    font-size: 1rem;
  }
}

@media (prefers-reduced-motion: reduce) {
  html {
    scroll-behavior: auto;
  }
}