For one Skyrizi 150 mg/mL pen or syringe, this page's September 26, 2026 Reno RxGo discount-listing sample ranges from $24,035.62 to $24,606.75. This is a dated local listing for one unit, not a guaranteed nationwide price or the cost of every dosing schedule. Compare the exact prescribed presentation on the RxDiff Skyrizi page and confirm the final price with the pharmacy.
Skyrizi, 1 pen or syringe 150 mg/ml (30-day supply), Reno, NV 89501, as of September 26, 2026: Walgreens Specialty $24,035.62; Cancer Care Specialists $24,463.72; Valley $24,606.75. Source: RxGo pricing data. Prices are estimates and vary by pharmacy, ZIP code and day. See current prices on the Skyrizi page.
| Source | Lowest price shown | Pharmacy |
|---|---|---|
| RxDiff (RxGo pricing data) — Lowest named pharmacy | $24,035.62 | Walgreens Specialty |
| SingleCare — Lowest price shown | $21,935 | Smiths |
Compared: Skyrizi 150 mg/mL pen x 1.
We compared the same drug, strength, quantity and ZIP code on each source on September 26, 2026. We did not compare GoodRx. RxGo may list additional pharmacies without names. Prices are estimates, vary by pharmacy, ZIP and day, and either source can be lower on a given day. See current prices on the RxDiff drug page.
Skyrizi contains risankizumab-rzaa. What someone pays without insurance depends on the exact presentation, quantity, pharmacy, location, and current assistance terms. The snapshot above is a dated example, not a guaranteed quote.
Match the prescribed pen or syringe, strength, and quantity before comparing. Ask the pharmacy to confirm stock, the final amount, and whether any payment option applies. Coverage, authorization, and program requirements can change, so check current terms directly with the plan or program provider.
Skyrizi and other biologic medicines can differ in ingredients, approved uses, administration, and coverage. A lower quote does not establish that another medicine is appropriate. Do not change treatment based only on price.
Prices vary by pharmacy and can change. Compare a current quote for your exact prescription on the RxDiff Skyrizi page.
Ask your pharmacist or plan which current terms apply to your prescription before filling it.
An insured copay, a pharmacy cash quote, and a discount-card listing can reflect different contracts. Pharmacy benefit managers (PBMs) negotiate formulary terms and manufacturer rebates that may not lower the price someone pays at the counter. Deductibles and prior authorization can further change an individual's share.
Pharmacies may use different markups and purchasing terms for this injectable medicine. A plan may also require a specialty pharmacy, whose delivery arrangements, network status, and stock can affect the final quote.
Skyrizi is a biologic, and there is currently no generic version to substitute at the pharmacy. Without a lower-priced equivalent of the same medicine, coverage and assistance eligibility can matter greatly. Ask the dispensing pharmacy for the current total, including any applicable service or delivery charges.
Skyrizi contains risankizumab-rzaa and does not currently have a generic equivalent available for substitution. Biologics are not copied as traditional generics; a comparable product would require its own biosimilar approval, and another psoriasis treatment is not automatically interchangeable. This limits the option of asking for the same medicine in a cheaper generic form. If the price is a barrier, discuss clinically appropriate alternatives with your prescriber and compare the coverage of the actual prescription.
Compare discount-card terms. Request a quote for the exact prescribed pen or syringe and ask whether the dispensing pharmacy accepts the card. Check the final amount and whether the offer can be used instead of insurance.
Ask about manufacturer support. Check current Skyrizi copay and patient-assistance programs with their operator. Commercial insurance, income, and other eligibility rules may differ, so do not assume an offer applies to an uninsured prescription.
Compare pharmacies. Request current quotes for the same presentation, quantity, and ZIP code from pharmacies allowed to fill your prescription. Confirm stock, pickup or delivery fees, and the total before moving a prescription.
Shop specialty channels when allowed. Ask your plan which specialty pharmacies are in network and whether you can choose among them. Compare delivery arrangements and out-of-pocket costs for the same fill rather than a different dosing schedule.
Appeal a coverage denial. If prior authorization is denied, request the plan's written reason and appeal instructions. Ask your prescriber to help provide medical documentation or seek an exception when appropriate; approval is not guaranteed.
Program availability, eligibility, and terms can change. Check current terms directly with the program provider and ask your plan or pharmacist how they apply to your prescription.
Ask your plan whether authorization or other coverage requirements apply, and ask your prescriber or pharmacist which documentation or next steps are relevant to your individual prescription.
Price alone does not determine whether a medicine is suitable. Ask your prescriber to discuss the options appropriate for your circumstances.
Compare current quotes for the exact prescription and ask your plan or pharmacist about applicable coverage terms. Do not change treatment based on a price comparison.
Ask the program provider directly whether assistance is currently available and whether its terms apply to you. Check your plan or program terms; eligibility and application requirements can change.
Follow the directions on your prescription and ask your pharmacist or prescriber about product information and current costs.
Ask the program provider about current eligibility and application steps. Your plan, program provider, and pharmacist can explain what information to check.
Compare a current quote on the RxDiff Skyrizi page. Ask your pharmacist or plan about any discount or assistance terms before relying on them.
Check a current price for your prescription.
Compare Skyrizi prices on RxDiff →Program terms and eligibility can change. Ask the program provider directly whether its current terms apply to you.
Coverage varies by plan. Check your plan documents or contact your insurer and pharmacist about your prescription.
Prices vary by pharmacy; see current prices on the RxDiff Skyrizi page. Ask your pharmacist or program provider about current terms.
Prices vary by pharmacy and prescription. Check a current quote on the RxDiff Skyrizi page and ask your pharmacist or plan about any applicable terms.
For FDA approval information, search the FDA Drugs@FDA database for Skyrizi (risankizumab-rzaa).
For product information, see the DailyMed Skyrizi (risankizumab-rzaa) label. For general background on biologic treatments for psoriasis, see the American Academy of Dermatology resource.
Medical Disclaimer: This content is for informational purposes only and does not constitute medical or financial advice. Prices vary by pharmacy; check a current quote for your prescription. Consult your healthcare provider or pharmacist about your medications and treatment plan.
Editorial disclosure: RxDiff Editorial Team guides are for prescription price and savings information. They are not medical advice. Verify current prices, eligibility, and health information with the pharmacy, prescriber, pharmacist, or official source.