Omeprazole at CVS runs $18–$35 without a coupon. Walgreens pharmacy prices for the same generic omeprazole 20 mg are slightly lower — typically $16–$32 — but both pharmacies charge far more than Walmart or Kroger pharmacy for the same medication. With a free discount card, omeprazole cost drops to $10–$15 at both CVS and Walgreens.
For drug safety details on omeprazole, see the MedlinePlus omeprazole fact sheet — a reliable NIH consumer resource for prescription medication information.
This guide compares omeprazole prices at CVS, Walgreens, Walmart pharmacy, Kroger pharmacy, Costco, and Rite Aid — and shows you exactly how to find the cheapest option for your course of treatment.
Compare real-time omeprazole prices near you on RxDiff before filling your next prescription.
| Pharmacy | Omeprazole 20mg (30ct) — No Coupon | With Discount Card |
|---|---|---|
| The store | $18–$35 | ~$10–$15 |
| Walgreens | $16–$32 | ~$10–$14 |
| Walmart | $4–$10 | ~$4–$8 |
| The grocery chain | $8–$14 | ~$8–$12 |
| Rite Aid | $18–$36 | ~$11–$16 |
| Costco | $6–$12 | ~$6–$10 |
Prices vary significantly by pharmacy location, dosage, and quantity. Depending on the pharmacy you use, the cost of omeprazole can differ by $25 or more for the same 30-day supply. Comparing prices at nearby pharmacies before you fill — rather than assuming your usual pharmacy has the best deal — can deliver significant savings over time.
The FDA classifies omeprazole as a generic drug equivalent to the brand-name Prilosec — meaning every pharmacy's generic omeprazole contains the same active ingredient at the same strength. Generic and brand-name prices differ, but generic quality does not.
Omeprazole without insurance is still very affordable because it is one of the most widely produced generic drugs in the US. The cheapest option at most pharmacy locations is the generic version — not the brand-name Prilosec OTC or prescription Prilosec — which contains the same active ingredient at a lower price.
To find the cheapest pharmacy for omeprazole without insurance, use GoodRx, SingleCare, WellRx, or BuzzRx to check current omeprazole prices at pharmacies near you. These free discount tools show you generic and brand-name prices at participating pharmacies — letting you find the cheapest option with one search before you leave home.
Omeprazole without insurance through mail-order pharmacy services can also deliver lower per-pill pricing than retail pharmacy locations. Using a mail-order pharmacy for a 90-day supply of omeprazole instead of monthly 30-day fills reduces your overall cost and the number of trips to the pharmacy counter.
The OTC version of the medication — sold as The over-the-counter version — is available without a prescription at any pharmacy. It and generic version it contain the same active ingredient at the same 20 mg strength. The main difference is packaging and price: the OTC version is more expensive per tablet than affordable the drug purchased with a prescription coupon.
If you take the lower-cost regularly for a chronic condition like GERD or frequent heartburn, ask your doctor or pharmacist about switching from the OTC version to a prescription. With a prescription for lower-cost version the medication and a free savings card, you can often access a lower cost per tablet than the OTC version at The store pharmacies or The chain pharmacy.
The prescription medication it is also available in 10 mg and 40 mg dosages that are not available OTC. The 40 mg version of the drug is commonly prescribed for erosive esophagitis and conditions requiring stronger acid production suppression. Ask your licensed healthcare professional which dosage is appropriate for your specific diagnosis.
Comparing prices at nearby pharmacies reveals that Walmart the location consistently undercuts The chain and The drugstore chain on the affordable version cost. If your nearest the chain location is a Walmart or It, you may already be accessing the best the medication pricing in your area without needing a coupon.
Costco the store is another competitive option for it. The warehouse club's the drugstore is open to non-members for your fills in most states, and its the drug pricing often matches or beats Walmart. A 90-day supply of affordable the lower-cost at The store can deliver significant savings compared to monthly fills at The store or The chain the location.
Rite Aid the medication pricing is similar to The the location chain — higher than Walmart or The grocery chain at the retail price but competitive when a free card is applied. Check The chain prices on RxDiff alongside The chain and It to see which the chain location offers the best deal for your specific quantity and dosage.
Prescription coupons and discount cards are free and accepted at The chain pharmacies, It, and most other major the location chains. To use one, search for the inexpensive version on the savings card website or app, enter your zip code, and select your preferred the chain location. The app shows you the discounted the medication price at each nearby the store so you can compare before filling.
The Rx discount code from GoodRx or SingleCare is shown on-screen — you present it to the the the drugstore staff on your phone or print it. The discount replaces your insurance copay for that fill. Savings programs like these cannot be combined with insurance for the same prescription, but when the savings code price is lower than your copay, it's almost always better to use the the discount.
Ask your your the pharmacy staff which option is cheaper for your specific it prescription: your insurance copay or the discount tool price. A the it staff at any The store or The drugstore chain can run both prices through the system and tell you which to use. This is an easy conversation that can help lower the cost of the drug immediately.
Also check whether your the drugstore offers its own savings programs. The the location chain ExtraCare and The chain myWalgreens both offer occasional discounts and savings on affordable prescriptions like the lower-cost. These loyalty programs can stack additional savings on top of your regular free card price in some cases.
The the common strength the lower-cost tablet is the standard dosage for most heartburn and acid reflux treatment. It is the most widely available and lowest-priced dosage at The the store chain pharmacies, The chain the location, and all other major chains. Most savings programs and discount coupons are calculated based on the the standard dose dosage.
If your doctor has prescribed the the higher dose version of the medication for a more severe condition — such as a stomach ulcer or Zollinger-Ellison syndrome — expect to pay slightly more per capsule, but the lower-cost version version of it remains inexpensive even at the stronger tablet. Prices vary by the chain location, so compare the the higher dose the drug price at multiple local pharmacies using RxDiff.
The 10 mg dosage of the affordable is less commonly prescribed and may not be available at every the store. Check with your your pharmacy personnel or use an online the drugstore search to confirm availability before requesting a 10 mg the medication your Rx from your healthcare professional.
Affordable the medication is on the formulary of nearly every your plan plan as a preferred lower-cost. Most plans cover it at the lowest cost tier, meaning your copay is typically $0–$5 for a 30-day supply. If your plan has a high deductible that you haven't met yet, your out-of-pocket cost before meeting the deductible may be higher — making a free card the better option during that period.
Medicare plans may cover it under Part D drug coverage. Medicare plans generally place inexpensive version the drug at a low copay tier, though coverage depends on your specific plan's formulary. If your Medicare plan does not cover the affordable, or if your copay exceeds the savings card price, use a GoodRx savings code instead — you cannot combine Medicare drug coverage and a lower price tool for the same fill, but you can choose whichever gives you the lower price.
Comparing prices with and without your insurance coverage for the medication takes about 60 seconds using RxDiff. Enter your it your fill details, zip code, and the tool shows current cash prices at nearby pharmacies side by side — so you can make an informed decision before you fill.
RxDiff compares the lower-cost prices at The chain, It, Walmart, The store, and other pharmacies near you — free, instant, no account needed.
Compare It Prices on RxDiffAt The the drugstore chain, affordable the medication this dosage (30 capsules) costs $18–$35 without a the price reduction. The chain the location runs slightly lower at $16–$32. Using a free GoodRx the card at either the chain brings it to $10–$15 per month. Walmart and It the store prices are lower still — often $4–$10 without any savings code — making them the cheapest option if you have one nearby.
Often, yes. A your Rx for lower-cost the lower-cost version the common strength with a savings the lower price typically costs $10–$15 per month — less than the $14–$22 you'd pay for a The over-the-counter version 42-count box at The chain or It. If you take the medication long-term for heartburn or acid reflux, ask your doctor about a medication to access the lower cost version through your the drugstore.
Walmart the chain consistently has the lowest the drug prices among major chains — often $4–$10 per month without a the card. The warehouse club and The grocery chain are also very competitive on the affordable pricing. The store and The drugstore chain have higher retail the medication prices but become competitive when you apply a free GoodRx or SingleCare free card, bringing the cost down to $10–$15. Always compare prices at local pharmacies using RxDiff first.
The drug is a proton pump inhibitor (PPI) used to treat heartburn, acid reflux, GERD, stomach ulcers, and esophageal conditions caused by excess stomach acid. It reduces acid production in the stomach. The lower-cost is available both as a your fill medication (affordable version the medication, Prilosec) and as an OTC version for frequent heartburn. Always consult your doctor or the it staff about the right dosage and duration for your course of treatment.
Yes — both The chain pharmacies and It accept GoodRx, SingleCare, WellRx, and other the drug price reduction coupons. Present the savings code at the the store counter when dropping off your the drug your Rx. The your the pharmacy staff will apply the the lower price price instead of the retail price — no membership required. Check the GoodRx app for the current the affordable price at your specific the drugstore location before going in.
Yes — it has been available as a inexpensive version drug for over 20 years. Affordable the drug contains the same active ingredient at the same strength as brand-name Prilosec. The OTC version (over-the-counter omeprazole) costs more per tablet than the Rx value in most cases and is FDA-approved as bioequivalent. Lower-cost the lower-cost version is available at every major the location including The store, The drugstore chain, Walmart the chain, The store, The drugstore, and The store. It is also available as an online the store order through most mail-order services.
The medication prices shown are estimates and vary by the drugstore location, date, and supply. Always verify current prices using RxDiff or your the location's app before filling. This article is for informational purposes only and does not constitute medical advice. Consult your doctor or licensed healthcare professional before starting, stopping, or changing your it dosage or course of treatment.
Omeprazole is a widely used prescription drug for acid-related conditions. As a common prescription treatment, its prescription prices are among the lowest of any medication class. A PPIs medication like omeprazole has the lowest price when purchased as a generic rather than a brand-name product. These savings can help cover the cost of your other medications. Compare prescription prices at nearby pharmacies to find the best prescription price for your specific dosage and supply length.