How to Save on Enhertu
Use the free RxDiff discount card to save up to 80% on Enhertu at pharmacies near you. Compare prices at CVS, Walgreens, Walmart, Costco, and thousands of independent pharmacies — no insurance or account required.
About Enhertu
Enhertu is administered intravenous.
What is Enhertu used for?
According to FDA labeling: Is a HER2-directed antibody and topoisomerase inhibitor conjugate indicated for: HER2-Positive Early Breast Cancer as neoadjuvant treatment of adult patients with HER2-positive (IHC 3+ or ISH+) Stage II or III breast cancer, as determined by an FDA-authorized test followed by a taxane, trastuzumab, and pertuzumab (THP). as adjuvant treatment of adult patients with HER2-positive (IHC 3+ or ISH+) breast cancer who have residual invasive disease following neoadjuvant trastuzumab (with or without pertuzumab) and taxane-based treatment.
Important Safety Information
Eutropenia: Monitor complete blood counts prior to initiation of ENHERTU and prior to each dose, and as clinically indicated. Manage through treatment interruption or dose reduction.
Drug information sourced from the FDA. This is not medical advice — consult your doctor or pharmacist before starting or changing any medication.
Enhertu Prices Near You — 1 100 mg vial
Lowest price found: $3259.07 at 137 MOTT PHARMACY, INC.. Prices shown are with a free RxDiff discount card — no insurance needed.
| Pharmacy | Price with RxDiff Card |
|---|---|
| 137 MOTT PHARMACY, INC. | $3259.07 |
| MORRISTOWN | $3272.85 |
| DUANE READE | $3393.73 |
| WALGREENS SPECIALTY | $3393.73 |
| CVS INSIDE TARGET | $3470.55 |
| CVS | $3470.55 |
| VONS | $3471.63 |
| ACME | $3471.63 |
Prices vary by location and dosage. Use the search above to see real-time Enhertu prices at pharmacies near your zip code.
Frequently Asked Questions About Enhertu
How much does Enhertu cost without insurance?
Enhertu prices near you range from $3259.07 to $3591.34 with a free RxDiff discount card (1 100 mg vial). Prices vary by pharmacy — use the comparison above to find the cheapest option near your ZIP code.
Where is Enhertu cheapest near me?
The lowest Enhertu price near you is $3259.07 with a free RxDiff discount card. The comparison above shows all 15 participating pharmacies sorted cheapest to most expensive.
Is there a generic version of Enhertu?
Yes — the generic name for Enhertu is fam-trastuzumab deruxtecan-nxki. Generic versions contain the same active ingredient and are FDA-approved, often at a significantly lower cost. Use RxDiff to compare Enhertu vs generic fam-trastuzumab deruxtecan-nxki prices at pharmacies near you.
Do I need insurance to use RxDiff?
No. RxDiff is completely free and works without insurance. In many cases, RxDiff prices are lower than insurance copays — making it worth checking even if you have coverage.
Tips for Saving More on Enhertu
- Compare every pharmacy — Enhertu prices can vary dramatically by location. Warehouse pharmacies like Costco and Walmart often have the lowest cash prices on generics.
- Request a 90-day supply — Filling 90 days instead of 30 typically reduces the per-day cost, especially at mail-order and warehouse pharmacies.
- Use the free RxDiff discount card — Works at 70,000+ pharmacies with no sign-up or insurance required. In many cases the discount card price beats your insurance copay.
- Check for manufacturer savings programs — Brand-name medications may have copay cards that reduce your cost to $0–$5 per month with commercial insurance. See the manufacturer coupons page for available programs.
- Ask your doctor about alternatives — If Enhertu is expensive, a therapeutically equivalent generic or a different drug in the same class may cost significantly less. Always ask your prescriber before switching.
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