How to Save on Methotrexate
Use the free RxDiff discount card to save up to 80% on Methotrexate at pharmacies near you. Compare prices at CVS, Walgreens, Walmart, Costco, and thousands of independent pharmacies — no insurance or account required.
About Methotrexate
Methotrexate is classified as a Folate Analog Metabolic Inhibitor, administered oral.
What is Methotrexate used for?
According to FDA labeling: Methotrexate tablets are a diydrofolate reductase inhibitor indicated for the: Treatment of adults and pediatric patients with acute lymphoblastic leukemia (ALL) as part of a combination chemotherapy maintenance regimen, Treatment of adults with mycosis fungoides, Treatment of adults with relapsed or refractory non-Hodgkin lymphoma as part of a metronomic combination regimen, Treatment of adults with rheumatoid arthritis, Treatment of pediatric patients with polyarticular juvenile idiopathic arthritis (pJIA), Treatment of adults with severe psoriasis
Important Safety Information
5 WARNINGS AND PRECAUTIONS, Serious Infections : Monitor patients for infection during and after treatment with methotrexate. Withhold or discontinue methotrexate for serious infections as appropriate.
Drug information sourced from the FDA. This is not medical advice — consult your doctor or pharmacist before starting or changing any medication.
Methotrexate Prices Near You — 48 2.5 mg tablet
Lowest price found: $14.26 at ANTHONY'S. Prices shown are with a free RxDiff discount card — no insurance needed.
| Pharmacy | Price with RxDiff Card |
|---|---|
| ANTHONY'S | $14.26 |
| GOODWILL | $14.26 |
| DIPLOMAT CHEMISTS INC | $14.26 |
| KENNEDY DRUGS | $15.86 |
| 137 MOTT PHARMACY, INC. | $16.36 |
| CENTRAL | $16.86 |
| MORRISTOWN | $20.83 |
| ACME | $25.52 |
Prices vary by location and dosage. Use the search above to see real-time Methotrexate prices at pharmacies near your zip code.
Frequently Asked Questions About Methotrexate
How much does Methotrexate cost without insurance?
Methotrexate prices near you range from $14.26 to $55.04 with a free RxDiff discount card (48 2.5 mg tablet). Prices vary by pharmacy — use the comparison above to find the cheapest option near your ZIP code.
Where is Methotrexate cheapest near me?
The lowest Methotrexate price near you is $14.26 with a free RxDiff discount card. The comparison above shows all 15 participating pharmacies sorted cheapest to most expensive.
Do I need insurance to use RxDiff?
No. RxDiff is completely free and works without insurance. In many cases, RxDiff prices are lower than insurance copays — making it worth checking even if you have coverage.
Tips for Saving More on Methotrexate
- Compare every pharmacy — Methotrexate prices can vary dramatically by location. Warehouse pharmacies like Costco and Walmart often have the lowest cash prices on generics.
- Request a 90-day supply — Filling 90 days instead of 30 typically reduces the per-day cost, especially at mail-order and warehouse pharmacies.
- Use the free RxDiff discount card — Works at 70,000+ pharmacies with no sign-up or insurance required. In many cases the discount card price beats your insurance copay.
- Check for manufacturer savings programs — Brand-name medications may have copay cards that reduce your cost to $0–$5 per month with commercial insurance. See the manufacturer coupons page for available programs.
- Ask your doctor about alternatives — If Methotrexate is expensive, a therapeutically equivalent generic or a different drug in the same class may cost significantly less. Always ask your prescriber before switching.
Related Medications
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