How to Save on Xiidra
Use the free RxDiff discount card to save up to 80% on Xiidra at pharmacies near you. Compare prices at CVS, Walgreens, Walmart, Costco, and thousands of independent pharmacies — no insurance or account required.
About Xiidra
Xiidra is classified as a Lymphocyte Function-Associated Antigen-1 Antagonist, administered ophthalmic.
What is Xiidra used for?
According to FDA labeling: Xiidra ® (lifitegrast ophthalmic solution) 5% is indicated for the treatment of the signs and symptoms of dry eye disease (DED). Xiidra (lifitegrast ophthalmic solution) 5% is a lymphocyte function-associated antigen-1 (LFA-1) antagonist indicated for the treatment of the signs and symptoms of dry eye disease (DED).
Drug information sourced from the FDA. This is not medical advice — consult your doctor or pharmacist before starting or changing any medication.
Xiidra Prices Near You — 60 5 % droperette
Lowest price found: $714.35 at 137 MOTT PHARMACY, INC.. Prices shown are with a free RxDiff discount card — no insurance needed.
| Pharmacy | Price with RxDiff Card |
|---|---|
| 137 MOTT PHARMACY, INC. | $714.35 |
| MORRISTOWN | $717.57 |
| DUANE READE | $747.09 |
| WALGREENS SPECIALTY | $747.09 |
| VONS | $764.48 |
| ACME | $764.48 |
| ANTHONY'S | $766.98 |
| GOODWILL | $766.98 |
Prices vary by location and dosage. Use the search above to see real-time Xiidra prices at pharmacies near your zip code.
Frequently Asked Questions About Xiidra
How much does Xiidra cost without insurance?
Xiidra prices near you range from $714.35 to $788.64 with a free RxDiff discount card (60 5 % droperette). Prices vary by pharmacy — use the comparison above to find the cheapest option near your ZIP code.
Where is Xiidra cheapest near me?
The lowest Xiidra price near you is $714.35 with a free RxDiff discount card. The comparison above shows all 15 participating pharmacies sorted cheapest to most expensive.
Is there a generic version of Xiidra?
Yes — the generic name for Xiidra is lifitegrast. Generic versions contain the same active ingredient and are FDA-approved, often at a significantly lower cost. Use RxDiff to compare Xiidra vs generic lifitegrast prices at pharmacies near you.
Do I need insurance to use RxDiff?
No. RxDiff is completely free and works without insurance. In many cases, RxDiff prices are lower than insurance copays — making it worth checking even if you have coverage.
Tips for Saving More on Xiidra
- Compare every pharmacy — Xiidra prices can vary dramatically by location. Warehouse pharmacies like Costco and Walmart often have the lowest cash prices on generics.
- Request a 90-day supply — Filling 90 days instead of 30 typically reduces the per-day cost, especially at mail-order and warehouse pharmacies.
- Use the free RxDiff discount card — Works at 70,000+ pharmacies with no sign-up or insurance required. In many cases the discount card price beats your insurance copay.
- Check for manufacturer savings programs — Brand-name medications may have copay cards that reduce your cost to $0–$5 per month with commercial insurance. See the manufacturer coupons page for available programs.
- Ask your doctor about alternatives — If Xiidra is expensive, a therapeutically equivalent generic or a different drug in the same class may cost significantly less. Always ask your prescriber before switching.
Related Medications
These medications are in the Lymphocyte Function-Associated Antigen-1 Antagonist class.