How to Save on Xyrem
Use the free RxDiff discount card to save up to 80% on Xyrem at pharmacies near you. Compare prices at CVS, Walgreens, Walmart, Costco, and thousands of independent pharmacies — no insurance or account required.
About Xyrem
Xyrem is classified as a Central Nervous System Depressant, administered oral.
What is Xyrem used for?
According to FDA labeling: Xyrem is indicated for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients 7 years of age and older with narcolepsy. Xyrem is a central nervous system depressant indicated for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients 7 years of age and older with narcolepsy .
Important Safety Information
5 WARNINGS AND PRECAUTIONS, CNS depression: Use caution when considering the concurrent use of Xyrem with other CNS depressants 1 ).
Drug information sourced from the FDA. This is not medical advice — consult your doctor or pharmacist before starting or changing any medication.
Xyrem Prices Near You — 30 ML of 500 mg/ml solution
Lowest price found: $1196.31 at 137 MOTT PHARMACY, INC.. Prices shown are with a free RxDiff discount card — no insurance needed.
| Pharmacy | Price with RxDiff Card |
|---|---|
| 137 MOTT PHARMACY, INC. | $1196.31 |
| MORRISTOWN | $1201.04 |
| DUANE READE | $1248.35 |
| WALGREENS SPECIALTY | $1248.35 |
| VONS | $1277.20 |
| ACME | $1277.20 |
| ANTHONY'S | $1279.70 |
| GOODWILL | $1279.70 |
Prices vary by location and dosage. Use the search above to see real-time Xyrem prices at pharmacies near your zip code.
Frequently Asked Questions About Xyrem
How much does Xyrem cost without insurance?
Xyrem prices near you range from $1196.31 to $1349.80 with a free RxDiff discount card (30 ML of 500 mg/ml solution). Prices vary by pharmacy — use the comparison above to find the cheapest option near your ZIP code.
Where is Xyrem cheapest near me?
The lowest Xyrem price near you is $1196.31 with a free RxDiff discount card. The comparison above shows all 15 participating pharmacies sorted cheapest to most expensive.
Is there a generic version of Xyrem?
Yes — the generic name for Xyrem is sodium oxybate. Generic versions contain the same active ingredient and are FDA-approved, often at a significantly lower cost. Use RxDiff to compare Xyrem vs generic sodium oxybate prices at pharmacies near you.
Do I need insurance to use RxDiff?
No. RxDiff is completely free and works without insurance. In many cases, RxDiff prices are lower than insurance copays — making it worth checking even if you have coverage.
Tips for Saving More on Xyrem
- Compare every pharmacy — Xyrem prices can vary dramatically by location. Warehouse pharmacies like Costco and Walmart often have the lowest cash prices on generics.
- Request a 90-day supply — Filling 90 days instead of 30 typically reduces the per-day cost, especially at mail-order and warehouse pharmacies.
- Use the free RxDiff discount card — Works at 70,000+ pharmacies with no sign-up or insurance required. In many cases the discount card price beats your insurance copay.
- Check for manufacturer savings programs — Brand-name medications may have copay cards that reduce your cost to $0–$5 per month with commercial insurance. See the manufacturer coupons page for available programs.
- Ask your doctor about alternatives — If Xyrem is expensive, a therapeutically equivalent generic or a different drug in the same class may cost significantly less. Always ask your prescriber before switching.
Related Medications
These medications are in the Central Nervous System Depressant class.
More X Medications
Other medications starting with X that you can compare on RxDiff.